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Molecular Profiling Facility (Penn)

eagle-i ID


Resource Type

  1. Core Laboratory


  1. Resource Description
    "The Penn Molecular Profiling Facility provides instrumentation and expertise for DNA and RNA profiling. Microarrays and other highly parallel technologies provide the means for measuring the identity and abundance of DNA and RNA for targeted genes, or the whole genome, in a biological sample. The Facility offers a range of cost and performance options suitable for a variety of experimental questions. Molecular assays are critical to many aspects of basic, clinical, and population research, including molecular stratification of patients entering clinical protocols, molecular epidemiological and pharmacogenetic studies, as well as longitudinal follow-up of patients in clinical investigations. Since molecular technologies and instrumentation are evolving rapidly, the centralization of molecular testing services within this core facilitates utilization of leading-edge molecular analyses by the investigators. Because some assays are used for clinical decisions during clinical trials, tests are meticulously designed and performed with strict attention to the prevention of polymerase chain reaction (PCR) contamination. The Facility is a fully equipped molecular biology laboratory staffed by experienced individuals in developing and performing molecular biological assays. While the Facility staff performs most of the assays, investigator-performed studies are actively encouraged through the sharing of Facility procedures, individualized training of investigators or their technical staff, and use of core equipment. The Facility Director and the Technical Director are available to talk with investigators to explore how the services of the facility can enhance or design their specific research projects. We invite investigators to meet with us in the planning stages of their studies, especially before grant submissions, to discuss services that the core can provide, such as budget information and a description of the core for the resources section of the grant, as well as to plan collection and handling of the specimens for the study. The Facility is happy to custom design assays to fit an investigator's needs."
  2. Additional Name
    Penn Genomic Analysis Core
  3. Affiliation
    Perelman School of Medicine
  4. Affiliation
    Department of Genetics, University of Pennsylvania
  5. Affiliation
    Penn Genomics Analysis Core
  6. Affiliation
    Biomedical Research Core Facilities
  7. Performs Technique
    Multiplex bead assay
  8. Performs Technique
    SNP genotyping assay
  9. Performs Technique
    Real-time PCR
  10. Performs Technique
    Nucleic acid microarray assay
  11. Performs Technique
    miRNA expression assay
  12. Performs Technique
    Genotyping assay
  13. Website(s)
  14. Website(s)
  15. Director
    Ganguly, Tapan., PhD
  16. Secondary affiliation
    Abramson Cancer Center
Provenance Metadata About This Resource Record
  1. workflow state
  2. contributor
    ggrant (Gregory Grant)
  3. created
  4. creator
  5. modified
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016