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Biomarker quantification by mass spectrometry

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Resource Type

  1. Material analysis service


  1. Fee for service
  2. Resource Description
    "Rigorous quantification of serum, plasma or urinary biomarkers identified by metabolomics studies can be conducted using stable isotope dilution LC-SRM/MS methodology as described by Ciccimaro and Blair (Bioanalysis. 2010;2:311-341)."
  3. Related Resource
    Thermo Scientific TSQ Vantage triple quadrupole mass spectrometer with Waters nanoAcquity UPLC system
  4. Related Resource
    Thermo Scientific LTQ-XL ion trap mass spectrometer with Eksigent NanoLC system
  5. Related Resource
    Thermo TSQ Quantum Ultra triple quadrupole mass spectrometer with Waters 2690 Alliance series HPLC system
  6. Related Resource
    Agilent 6460 triple quadrupole mass spectrometer with Agilent 1200 HPLC system
  7. Service Provided by
    Translational Biomarker Core (Penn)
  8. Related Publication or Documentation
    Stable-isotope dilution LC–MS for quantitative biomarker analysis
  9. Related Publication or Documentation
    8-Oxo-2'-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress
  10. Related Publication or Documentation
    Quantification of key red blood cell folates from subjects with defined MTHFR 677C>T genotypes using stable isotope dilution liquid chromatography/mass spectrometry
  11. Related Technique
    Liquid chromatography-mass spectrometry
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Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016