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Villin-Cdx2 mice
eagle-i ID
http://eagle-i.itmat.upenn.edu/i/0000013a-f51b-a365-e44e-976d80000000
Resource Type
Properties
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Resource Description
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These transgenic mice overexpress Cdx2 in the small intestinal and colonic epithelium. Transgene expression was first detected by embryonic day 15.5. Adult transgene expression pattern is mosaic.
Phenotypes are linked to levels of transgene expression.
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Related Disease
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gastrointestinal system disease
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Related Publication or Documentation
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0000013a-f51d-178f-e44e-976d80000000
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Related Technique
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Microinjection
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Biological process studied
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Cell differentiation
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Genetic Alteration(s)
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Villin-(FLAG)-Cdx2 insertion
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Transgenic Construct
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0000013b-042b-9d6f-e44e-976d80000000
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Phenotype Findings
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Fat malabsorption
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Phenotype Findings
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Premature maturation of the intestinal epithelium
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Phenotype Findings
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Altered crypt organization
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Location
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0000013a-995d-34c1-d69a-d90d80000000
