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Adeno-associated viral vector services

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Resource Type

  1. Material production service


  1. Fee for service
  2. Resource Description
    "A number of novel AAV vectors were originally isolated and developed at Penn in the laboratory of Dr. James Wilson and first made available to investigators through the Penn Vector Core. Due to its close proximity to the Wilson laboratory, the Penn Vector Core is able to rapidly assimilate new vector technologies and make them available to its users. The Core offers a variety of novel serotype AAV vectors and additional vectors currently under development will be distributed through the Penn Vector. The Core currently offers 8 AAV vector serotypes, with additional serotypes also available. The tropism of selected AAV serotypes is shown in the following table with an X shown where efficacy has been demonstrated. For targets not listed, it may be necessary to conduct pilot serotype selection studies to determine the serotype of choice. We recommend serotype selection studies be performed in vivo since the in vitro transduction efficiencies of many of the serotypes below does not accurately reflect in vivo performance. For investigators wishing to discuss the serotype of choice for their application, please contact the Director of the Penn Vector Core. <b>AAV1</b>: skeletal muscle, heart, lung, CNS/eye <b>AAV2</b>: CNS/eye <b>AAV5</b>: lung, CNS/eye <b>AAV6</b>: skeletal muscle, heart, lung, CNS/eye, liver, adipose <b>AAV7</b>: skeletal muscle, CNS/eye, liver <b>AAV8</b>: skeletal muscle, CNS/eye, liver, adipose <b>AAV9</b>: skeletal muscle, heart, lung, CNS/eye, liver, adipose <b>AAVrh10</b>: skeletal muscle, lung, liver The Penn Vector Core is pleased to offer four scales of AAV production services."
  3. Service Fee URL
  4. Additional Name
    AAV vector services
  5. Service Provided by
    Vector Core (Penn)
  6. Website(s)
  7. Website(s)
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Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016