The University of Pennsylvania
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Transgenic lines were obtained by pronuclear injection into fertilized C57BL/6;SJLF1 hybrid oocytes. This line displays efficient deletion of <i>Foxa2</i> in the liver.
Related Publication or Documentation
Foxa2 integrates the transcriptional response of the hepatocyte to fasting
Biological process studied
Construct for hepatocyte-specific expression of Cre in mice
Blunting of hepatic transcriptional response to fasting
Reduced binding of glucocorticoid receptor to targets
Upregulation of Foxa1
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Mus <mouse, genus>
Organism or Virus
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