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Akt1loxP/loxP;Akt2loxP/loxP

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013c-7399-fdec-f162-a2b280000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    This strain can be used to develop tissue-specific Akt1 and Akt2 knockout mice.
  2. Additional Name
    Akt1lox <b>x</b> Akt2lox
  3. Related Disease
    diabetes mellitus
  4. Related Publication or Documentation
    Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1
  5. Related Publication or Documentation
    Akt2 is required for hepatic lipid accumulation in models of insulin resistance
  6. Parental Strain Name
    C57BL6
  7. Genetic Alteration(s)
    Akt2[tm1Mbb]
  8. Genetic Alteration(s)
    Floxed Akt1
  9. Location
    Birnbaum Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-01-25T16:26:36.683-05:00
  4. creator
    fcoldren
  5. modified
    2013-01-29T15:17:03.422-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016