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Liver-specific Akt2 KO

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013c-73b1-f7b9-f162-a2b280000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    Liver-specific Akt2 KO mice were created by injecting Akt2 <sup>loxP/loxP</sup> mice with adeno-associated virus expressing Cre recombinase under the control of the Tbg promoter (AAV-Tbg-Cre).
  2. Additional Name
    2LKO
  3. Related Disease
    type 2 diabetes mellitus
  4. Related Publication or Documentation
    Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1
  5. Parental Strain Name
    C57BL6
  6. Genetic Alteration(s)
    Akt2[tm1Mbb]
  7. Phenotype Findings
    Normal metabolism phenotype
  8. Location
    Birnbaum Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-01-25T16:52:26.815-05:00
  4. creator
    fcoldren
  5. modified
    2013-01-29T15:19:35.830-05:00

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016