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Dicer1(loxP/loxP);Villin-Cre

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013c-877e-011b-f162-a2b280000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    <i>Dicer1<sup>loxP/loxP</sup></i> conditional mutant mice (C57BL6) were crossed with Villin-Cre transgenic mice.
  2. Related Disease
    intestinal disease
  3. Related Publication or Documentation
    MicroRNAs Control Intestinal Epithelial Differentiation, Architecture, and Barrier Function
  4. Biological process studied
    Organ development
  5. Genetic Alteration(s)
    Floxed Dicer1
  6. Genetic Alteration(s)
    Villin-Cre
  7. Phenotype Findings
    Impaired growth
  8. Phenotype Findings
    Impaired fat absorption
  9. Phenotype Findings
    Impaired water retention
  10. Phenotype Findings
    Altered intestine morphology
  11. Phenotype Findings
    Decreased intestinal epithelial barrier function
  12. Location
    Kaestner Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-01-29T13:07:45.055-05:00
  4. creator
    fcoldren
  5. modified
    2013-02-08T16:43:07.888-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016