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Intestine-specific Foxa1;Foxa2 knockout
A series of crosses was used to produce mice with intestine-specific deletion of <i>Foxa1</i> and <i>Foxa2</i>. Foxa1 and Foxa2 proteins were absent from the small intestine, colon, and rectum.
Related Publication or Documentation
Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-Cells in mice
Biological process studied
Reduced body weight and slower growth rate
Defective goblet cell differentiation
Decreased enteroendocrine cell differentiation
Decreased differentiation of L- and D-cells
Inferred Types from the eagle-i Ontology (
What is an ontology?
Mus <mouse, genus>
Organism or Virus
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