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Crk(loxP/loxP); Nestin-Cre

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013c-c9c2-cd40-f162-a2b280000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    Nestin-Cre transgenic mice from Jackson laboratory were bred with floxed <i>Crk</i> mice.
  2. Additional Name
    Neuron-specific <i>Crk</i> knockout
  3. Related Publication or Documentation
    Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway
  4. Parental Strain Name
    C57BL/6 x 129SvEv
  5. Biological process studied
    Brain development
  6. Genetic Alteration(s)
    Floxed Crk
  7. Genetic Alteration(s)
    Nestin-Cre
  8. Phenotype Findings
    Reduced body weight
  9. Phenotype Findings
    Normal brain morphology
  10. Location
    Curran Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-02-11T10:00:54.929-05:00
  4. creator
    fcoldren
  5. modified
    2013-02-20T16:03:28.892-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016