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Ne-reelin

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013c-c9de-8bc4-f162-a2b280000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    Myc-tagged <i>reelin</i> under the control of the rat <i>nestin</i> intermediate-filament gene promoter was introduced into fertilized one-cell FvB mouse embryos by microinjection. Mice carrying <i>ne-reelin</i> express an additional source of reelin mRNA throughout the ventricular zone of the forebrain, midbrain, and cerebellum at E16.5. <i>ne-reelin</i> was present at levels of approximately 10% and 20% of the endogenous Reelin in two founder lines.
  2. Related Publication or Documentation
    Ectopic expression of reelin alters migration of sympathetic preganglionic neurons in the spinal cord
  3. Related Publication or Documentation
    Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice
  4. Parental Strain Name
    FVB
  5. Genetic Alteration(s)
    Ne-reelin
  6. Location
    Curran Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-02-11T10:28:11.402-05:00
  4. creator
    fcoldren
  5. modified
    2013-02-20T16:07:36.774-05:00

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016