eagle-i The University of PennsylvaniaThe University of Pennsylvania

Visceral epithelial abnormalities

eagle-i ID


Resource Type

  1. Mammal-specific phenotype


  1. Resource Description
    At 90-140 days of age, all mice have visceral/parietal (V/P) epithelial hyperplasia as well as interstitial fibrosis and cortical inflammation. There is diffuse effacement of foot processes along with visceral epithelial hyperplasia, despite the paucity of interstitial infiltrates. The pathology is observed prior to elevation of the BUN levels or histologic evidence of severe interstitial disease.
  2. Mammalian phenotype
    abnormal renal/urinary system morphology
Provenance Metadata About This Resource Record
    Copyright © 2016 by the President and Fellows of Harvard College
    The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016