eagle-i The University of PennsylvaniaThe University of Pennsylvania

Nephritis

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013c-df0e-0df4-f162-a2b280000000

Resource Type

  1. Mammal-specific phenotype

Properties

  1. Resource Description
    After 30 weeks of age, BUN levels frequently exceed 120 mg/dl.
  2. Resource Description
    At 116 days of age, moderately severe tubulointerstitial nephritis (3+) with interstitial mononuclear cell infiltration and tubular dilatation are observed in histologic sections.
  3. Resource Description
    Infiltrating leukocytes in kidneys are mainly macrophages and CD4<sup>+</sup> T cells.
  4. Resource Description
    Significantly greater improvement following long-term treatment from weaning with probucol than CoQ<sub>10</sub> was seen among both genders for nephritis score.
  5. Mammalian phenotype
    kidney inflammation
 
RDFRDF
 
Provenance Metadata About This Resource Record
    Copyright © 2016 by the President and Fellows of Harvard College
    The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016