eagle-i The University of PennsylvaniaThe University of Pennsylvania

Reduction of mutant phenotype under germfree conditions

eagle-i ID


Resource Type

  1. Mammal-specific phenotype


  1. Resource Description
    Although germfree (GF) conditions do not completely prevent the occurrence of kidney disease, there are significantly fewer positive animals at every age range tested, in comparison to mice raised under specific pathogen-free (SPF) conditions. Mice have a normal mitochondrial phenotype. There iss no evidence of podocyte effacement for GF mice (over 100 days of age).
  2. Mammalian phenotype
    phenotypic reversion
Provenance Metadata About This Resource Record
    Copyright © 2016 by the President and Fellows of Harvard College
    The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016