Impaired motor coordination

eagle-i ID

Resource Type

Properties

1. Resource Description

   At 10, 12, and 13 weeks of age, mice exhibit increased difficulty in traversing a vertical pole compared to wild-type animals. Furthermore, they show marked difficulty in coordinating the transition from the pole to the ground relative to wild-type animals.

2. Resource Description

   In rotarod testing at 11, 12, and 13 weeks of age, age-matched mice consistently perform worse than wild-type B6 mice.

3. Mammalian phenotype

   impaired coordination