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ErythronDB
eagle-i ID
http://eagle-i.itmat.upenn.edu/i/0000013d-8e1e-6b5f-2ed7-105480000000
Resource Type
Properties
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Related grant number
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NIDDK R01 DK 071116
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Related Software
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Strategies WDK
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Resource Description
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"The ErythronDB project is the result of a collaboration between the <b>Palis Lab (University of Rochester)</b> and the <b>Stoeckert Lab (University of Pennsylvania)</b>. The laboratory of Dr. Palis brings expertise in the cellular and molecular events underlying the ontogeny of hematopoiesis in the mammalian embryo. The laboratory of Dr. Stoeckert contributes state of the art computational and bioinformatics expertise.
The Erythron Database is a resource dedicated to facilitating better understanding of the cellular and molecular underpinnings of mammalian erythropoiesis. The resource is built upon a searchable database of gene expression in murine primitive and definitive erythroid cells at progressive stages of maturation.
ErythronDB allows users to identify sets of genes that are differentially expressed or exhibit similar levels or patterns of mRNA expression during erythrocyte development. Searches are also available for exploring networks of gene-interactions inferred from annotated expression data.
All ErythronDB strategies can easily be refined and expanded using the Strategies interface. Register to save and share strategies with others. Registration also provides access to a Basket, which allows users to interactively assemble a list of genes of interest from search strategy results."
Members from the <b>Palis Lab in the Department of Pediatrics, University of Rochester Medical Center</b> that developed ErythronDB are Paul D. Kingsley, Ph.D.; Jenna M. Frame, M.S.; Timothy P. Bushnell, Ph.D.; Jeffrey Malik, Ph.D.; Kathleen E. McGrath, Ph.D.; and James Palis, M.D..
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Used by
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Computational Biology and Informatics Laboratory
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Operating System
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Web based
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Data Input
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Gene expression data from all three lineages of murine erythropoiesis
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Topic
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Mus musculus
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Topic
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Erythropoiesis
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Related Publication or Documentation
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Ontogeny of erythroid gene expression
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Related Publication or Documentation
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Stat and interferon genes identified by network analysis differentially regulate primitive and definitive erythropoiesis
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Website(s)
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http://www.cbil.upenn.edu/ErythronDB/
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Developed by
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Stoeckert, Christian J Jr., PhD
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Developed by
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Greenfest-Allen, Emily., PhD
