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RX2

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013d-f99c-2c9e-2ed7-105480000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    CastX females were mated to a male with a double recombinant X chromosome that was <i>Mus musculus castaneus EiJ</i> at distal ends and 129S1/SvImJ in the middle region. The founding double recombinant male was the offspring of a mating between a CastX male and a mixed background female heterozygous for <i>Mus musculus castaneus EiJ</i> and 129S1/SvImJ. Female progeny with a CastX and the double recombinant X chromosome were mated with CastX males to maintain existing and to generate new recombinant alleles. To maintain existing or to generate new recombinant X chromosomes, males with the recombinant X chromosome were crossed to CastX females and then female progeny were mated with CastX males. Sperm was cryopreserved from RX2 mice.
  2. Related Publication or Documentation
    Nonrandom X chromosome inactivation is influenced by multiple regions on the murine X chromosome
  3. Biological process studied
    Regulation of gene expression, epigenetic
  4. Genetic Alteration(s)
    Double recombinant X chromosome
  5. Phenotype Findings
    X chromosome inactivation
  6. Location
    Bartolomei Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-04-11T11:00:32.600-04:00
  4. creator
    fcoldren
  5. modified
    2013-04-24T10:49:45.065-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016