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eagle-i ID


Resource Type

  1. Mus musculus


  1. Resource Description
    CastX females were mated to a male with a double recombinant X chromosome that was <i>Mus musculus castaneus EiJ</i> at distal ends and 129S1/SvImJ in the middle region. The founding double recombinant male was the offspring of a mating between a CastX male and a mixed background female heterozygous for <i>Mus musculus castaneus EiJ</i> and 129S1/SvImJ. Female progeny with a CastX and the double recombinant X chromosome were mated with CastX males to maintain existing and to generate new recombinant alleles. To maintain existing or to generate new recombinant X chromosomes, males with the recombinant X chromosome were crossed to CastX females and then female progeny were mated with CastX males. Sperm was cryopreserved from RX2 mice.
  2. Related Publication or Documentation
    Nonrandom X chromosome inactivation is influenced by multiple regions on the murine X chromosome
  3. Biological process studied
    Regulation of gene expression, epigenetic
  4. Genetic Alteration(s)
    Double recombinant X chromosome
  5. Phenotype Findings
    X chromosome inactivation
  6. Location
    Bartolomei Laboratory
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Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016