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Zp3dsCTCF

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013d-f9c2-f470-2ed7-105480000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    Mice harbor a transgene that expresses an RNA hairpin designed to target CTCF mRMA under the control of a promoter specific to growing oocytes specific to growing oocytes [<i>Zona pellucida 3</i>].
  2. Related Publication or Documentation
    Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development
  3. Related Publication or Documentation
    Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting
  4. Biological process studied
    Regulation of gene expression, epigenetic
  5. Genetic Alteration(s)
    Zp3-dsCTCF
  6. Phenotype Findings
    Transcriptional misregulation
  7. Phenotype Findings
    CTCF knockdown in oocytes
  8. Location
    Bartolomei Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-04-11T11:49:53.201-04:00
  4. creator
    fcoldren
  5. modified
    2013-04-24T10:50:48.726-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016