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DAF(-/-)/C3(-/-)
eagle-i ID
http://eagle-i.itmat.upenn.edu/i/0000013e-57fb-17da-2f2e-ad3380000000
Resource Type
Mus musculus
Properties
Resource Description
DAF<sup>-/-</sup> mice were crossed with C3<sup>-/-</sup> mice.
Additional Name
CD55(-/-)/C3(-/-)
Related Publication or Documentation
Complement-dependent enhancement of CD8+ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice
Related Publication or Documentation
Decay-accelerating factor regulates T-cell immunity in the context of inflammation by influencing costimulatory molecule expression on antigen-presenting cells
Related Publication or Documentation
Regulation of Toll-like receptor–mediated inflammatory response by complement in vivo
Related Publication or Documentation
Deficiency of decay-accelerating factor and complement receptor 1–related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg
Related Publication or Documentation
Retrovirus-mediated over-expression of decay-accelerating factor rescues Crry-deficient erythrocytes from acute alternative pathway complement attack
Biological process studied
Immune system process
Genetic Alteration(s)
CD55[tm1Song]
Genetic Alteration(s)
C3[tm1Hrc]
Phenotype Findings
Response to antigen restimulation
Phenotype Findings
Experimental autoimmune encephalomyelitis phenotype
Phenotype Findings
Normal cytokine level
Phenotype Findings
Response to acute LCMV infection
Location
Wen-Chao Song Laboratory
Inferred Types from the eagle-i Ontology (
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entity
continuant
independent_continuant
material_entity
Organism
Mus <mouse, genus>
Glires
Mammalia
Chordata
Vertebrata <Metazoa>
Rodentia
Organism or Virus
Thing
Provenance Metadata About This Resource Record
workflow state
Published
contributor
fcoldren
created
2013-04-29T19:25:14.207-04:00
creator
fcoldren
modified
2013-06-05T15:49:43.228-04:00