eagle-i The University of PennsylvaniaThe University of Pennsylvania
See it in Search
This page is a preview of the following resource. Continue onto eagle-i search using the button on the right to see the full record.

DAF(-/-)/C3(-/-)

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013e-57fb-17da-2f2e-ad3380000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    DAF<sup>-/-</sup> mice were crossed with C3<sup>-/-</sup> mice.
  2. Additional Name
    CD55(-/-)/C3(-/-)
  3. Related Publication or Documentation
    Complement-dependent enhancement of CD8+ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice
  4. Related Publication or Documentation
    Decay-accelerating factor regulates T-cell immunity in the context of inflammation by influencing costimulatory molecule expression on antigen-presenting cells
  5. Related Publication or Documentation
    Regulation of Toll-like receptor–mediated inflammatory response by complement in vivo
  6. Related Publication or Documentation
    Deficiency of decay-accelerating factor and complement receptor 1–related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg
  7. Related Publication or Documentation
    Retrovirus-mediated over-expression of decay-accelerating factor rescues Crry-deficient erythrocytes from acute alternative pathway complement attack
  8. Biological process studied
    Immune system process
  9. Genetic Alteration(s)
    CD55[tm1Song]
  10. Genetic Alteration(s)
    C3[tm1Hrc]
  11. Phenotype Findings
    Response to antigen restimulation
  12. Phenotype Findings
    Experimental autoimmune encephalomyelitis phenotype
  13. Phenotype Findings
    Normal cytokine level
  14. Phenotype Findings
    Response to acute LCMV infection
  15. Location
    Wen-Chao Song Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-04-29T19:25:14.207-04:00
  4. creator
    fcoldren
  5. modified
    2013-06-05T15:49:43.228-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016