eagle-i The University of PennsylvaniaThe University of Pennsylvania
See it in Search
This page is a preview of the following resource. Continue onto eagle-i search using the button on the right to see the full record.


eagle-i ID


Resource Type

  1. Mus musculus


  1. Resource Description
    DAF<sup>-/-</sup> mice were crossed with C3<sup>-/-</sup> mice.
  2. Additional Name
  3. Related Publication or Documentation
    Complement-dependent enhancement of CD8+ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice
  4. Related Publication or Documentation
    Decay-accelerating factor regulates T-cell immunity in the context of inflammation by influencing costimulatory molecule expression on antigen-presenting cells
  5. Related Publication or Documentation
    Regulation of Toll-like receptor–mediated inflammatory response by complement in vivo
  6. Related Publication or Documentation
    Deficiency of decay-accelerating factor and complement receptor 1–related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg
  7. Related Publication or Documentation
    Retrovirus-mediated over-expression of decay-accelerating factor rescues Crry-deficient erythrocytes from acute alternative pathway complement attack
  8. Biological process studied
    Immune system process
  9. Genetic Alteration(s)
  10. Genetic Alteration(s)
  11. Phenotype Findings
    Response to antigen restimulation
  12. Phenotype Findings
    Experimental autoimmune encephalomyelitis phenotype
  13. Phenotype Findings
    Normal cytokine level
  14. Phenotype Findings
    Response to acute LCMV infection
  15. Location
    Wen-Chao Song Laboratory
Provenance Metadata About This Resource Record
  1. workflow state
  2. contributor
  3. created
  4. creator
  5. modified
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016