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DAF(-/-)/CD59(-/-)/C3(-/-)

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013e-5825-8715-2f2e-ad3380000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    DAF<sup>-/-</sup>CD59<sup>-/-</sup> were crossed with C3<sup>-/-</sup> mice. The C3<sup>-/-</sup> line (G6 backcross) is from The Jackson Laboratory (Bar Harbor, ME). The C3<sup>−/−</sup> mouse was further backcrossed in-house to G11.
  2. Additional Name
    CD55(-/-)/CD59(-/-)/C3(-/-)
  3. Related Publication or Documentation
    Blocking Properdin, the Alternative Pathway, and Anaphylatoxin Receptors Ameliorates Renal Ischemia-Reperfusion Injury in Decay-Accelerating Factor and CD59 Double-Knockout Mice
  4. Genetic Alteration(s)
    CD55[tm1Song]
  5. Genetic Alteration(s)
    Cd59a[tm1Song]
  6. Genetic Alteration(s)
    C3[tm1Hrc]
  7. Phenotype Findings
    Renal ischemia-reperfusion injury
  8. Location
    Wen-Chao Song Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-04-29T19:34:50.630-04:00
  4. creator
    fcoldren
  5. modified
    2013-06-05T15:57:37.621-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016