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DAF(-/-)/CD59(-/-)
eagle-i ID
http://eagle-i.itmat.upenn.edu/i/0000013e-5c12-a5cf-2f2e-ad3380000000
Resource Type
Mus musculus
Properties
Resource Description
DAF<sup>-/-</sup> were cross-bred with CD59<sup>-/-</sup> mice.
Additional Name
CD55(-/-)/CD59(-/-)
Additional Name
DAF/CD59 d-KO
Related Publication or Documentation
Blocking Properdin, the Alternative Pathway, and Anaphylatoxin Receptors Ameliorates Renal Ischemia-Reperfusion Injury in Decay-Accelerating Factor and CD59 Double-Knockout Mice
Related Publication or Documentation
Critical protection from renal ischemia reperfusion injury by CD55 and CD59
Related Publication or Documentation
Crry, but not CD59 and DAF, is indispensable for murine erythrocyte protection in vivo from spontaneous complement attack
Website(s)
http://www.informatics.jax.org/allele/genoview/MGI:3581707?counter=7
Parental Strain Name
C57BL/6
Biological process studied
Immune system process
Genetic Alteration(s)
CD55[tm1Song]
Genetic Alteration(s)
Cd59a[tm1Song]
Phenotype Findings
Increased susceptibility to kidney reperfusion injury
Phenotype Findings
Abnormal complement pathway
Phenotype Findings
Hematopoietic system phenotype
Location
Wen-Chao Song Laboratory
Inferred Types from the eagle-i Ontology (
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entity
continuant
independent_continuant
material_entity
Organism
Mus <mouse, genus>
Glires
Mammalia
Chordata
Vertebrata <Metazoa>
Rodentia
Organism or Virus
Thing
Provenance Metadata About This Resource Record
workflow state
Published
contributor
fcoldren
created
2013-04-30T13:52:40.015-04:00
creator
fcoldren
modified
2016-02-17T17:18:28.137-05:00