fP(fl/fl)

eagle-i ID

Resource Type

Properties

1. Resource Description

   "A targeting vector was constructed where a loxP site was inserted upstream of exon 3, and a FRT flanked neomycin resistance cassette followed by a loxP site was inserted downstream of exon 5. Flp mediated recombination removed the neo cassette leaving exons 3 through 5 floxed." This strain is cryo-preserved.

2. Additional Name

   Cfp(fl/fl)

3. Additional Name

   Properdin flox/flox

4. Related Publication or Documentation

   Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury

5. Website(s)

   http://www.informatics.jax.org/javawi2/servlet/WIFetch?page=alleleDetail&key=621654

6. Parental Strain Name

   C57BL/6

7. Genetic Alteration(s)

   Cfp[tm2.1Song]

8. Location

   Wen-Chao Song Laboratory