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fP(fl/fl);EIIa-Cre

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000013e-5c1f-c232-2f2e-ad3380000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    <i>fP<sup>fl/fl</sup></i> mice were crossed with Ella-Cre transgenic mice (The Jackson Laboratory), which express Cre in oocytes and is often used as a universal deleter of floxed genes. Exons 3-5 of <i>Cfp</i> gene were deleted.
  2. Additional Name
    Cfp(flox/flox);EIIa-Cre
  3. Additional Name
    fP(flox/flox);EIIa-Cre<sup>+</sup>
  4. Related Publication or Documentation
    Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury
  5. Parental Strain Name
    mixed C57BL/6-129J
  6. Biological process studied
    Immune system process
  7. Genetic Alteration(s)
    Cfp[tm2.1Song]
  8. Genetic Alteration(s)
    Tg(EIIa-cre)C5379Lmgd
  9. Phenotype Findings
    Impaired complement alternative pathway
  10. Location
    Wen-Chao Song Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-04-30T14:07:24.112-04:00
  4. creator
    fcoldren
  5. modified
    2013-06-05T14:59:13.770-04:00

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016