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beta1/beta2 double KO

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/00000141-a31f-ca85-91c7-0c6080000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    These mice have targeted disruption of the gene for β1- and β2-adrenergic receptors and were generated by crossing β1 KO mice with β2 KO mice.
  2. Additional Name
    β1/β2 AR DKO
  3. Related Publication or Documentation
    Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling.
  4. Website(s)
    http://jaxmice.jax.org/strain/003810.html
  5. Biological process studied
    memory
  6. Genetic Alteration(s)
    Adrb1[tm1Bkk]
  7. Genetic Alteration(s)
    Adrb2[tm1Bkk]
  8. Location
    Steven Thomas Laboratory
 
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Provenance Metadata About This Resource Record

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016