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beta1/beta3 double KO

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/00000141-e19f-e8f4-91c7-0c6080000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    These mice have targeted disruption of the gene for β1- and β3-adrenergic receptors and were generated by crossing β1 KO mice with β3 KO mice.
  2. Additional Name
    beta1,3-less mice
  3. Additional Name
    β1/β3 AR DKO
  4. Related Publication or Documentation
    Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling.
  5. Parental Strain Name
    hybrid FVB/N × 129/Sv × C57BL/6 × DBA/2 background
  6. Biological process studied
    memory
  7. Genetic Alteration(s)
    Adrb1[tm1Bkk]
  8. Genetic Alteration(s)
    Adrb3[tm1Lowl]
  9. Phenotype Findings
    Brown adipose tissue phenotype
  10. Location
    Steven Thomas Laboratory
 
RDFRDF
 
Inferred Types from the eagle-i Ontology (What is an ontology?)
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-10-22T15:37:05.005-04:00
  4. creator
    apernot (Anne Claire Pernot)
  5. modified
    2013-10-29T09:48:17.124-04:00
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016