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beta1/beta2/beta3 triple KO

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/00000141-efbe-eef8-91c7-0c6080000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    These mice have targeted disruption of the gene for β1-, β2-, and β3-adrenergic receptors. "We thank [...] B. Kobilka and B. Lowell for providing stock for the β receptor KO mouse lines."
  2. Additional Name
    beta-less mice
  3. Related Publication or Documentation
    Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling.
  4. Parental Strain Name
    hybrid FVB/N × 129/Sv × C57BL/6 × DBA/2 background
  5. Biological process studied
    memory
  6. Genetic Alteration(s)
    Adrb1[tm1Bkk]
  7. Genetic Alteration(s)
    Adrb2[tm1Bkk]
  8. Genetic Alteration(s)
    Adrb3[tm1Lowl]
  9. Location
    Steven Thomas Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2013-10-25T09:18:42.509-04:00
  4. creator
    apernot (Anne Claire Pernot)
  5. modified
    2013-10-29T09:46:58.718-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016