CaMKII-Cre Tg

eagle-i ID

Resource Type

Properties

1. Resource Description

   "Mice homozygous for the transgenic insert are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. These transgenic mice express the Cre recombinase under the control of the mouse calcium/calmodulin-dependent protein kinase II alpha promoter. Cre recombinase expression is detected in the forebrain, specifically to the CA1 pyramidal cell layer in the hippocampus. When crossed with a strain containing loxP site flanked sequence of interest, Cre-mediated recombination occurs in the pyramidal cell layer."

2. Website(s)

   http://jaxmice.jax.org/strain/005359.html

3. Biological process studied

   Brain development

4. Biological process studied

   neurological system process

5. Genetic Alteration(s)

   Tg(Camk2a-cre)T29-1Stl

6. Location

   Steven Thomas Laboratory