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Y145F
eagle-i ID
http://eagle-i.itmat.upenn.edu/i/00000144-c2a5-3d7a-3e6a-4e4480000000
Resource Type
Mus musculus
Properties
Resource Description
Mice were generated expressing SLP76 containing a single mutation in Y145 to phenylalanine (Y145F mice).
Related Disease
vascular disease
Related Publication or Documentation
Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo
Related Publication or Documentation
Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76
Website(s)
http://www.informatics.jax.org/allele/key/57394
Parental Strain Name
C57BL/6
Biological process studied
Immune system process
Genetic Alteration(s)
Lcp2[tm3Gak]
Phenotype Findings
Abnormal negative Tcell selection
Location
Koretzky Laboratory
Inferred Types from the eagle-i Ontology (
What is an ontology?
)
entity
continuant
independent_continuant
material_entity
Organism
Mus <mouse, genus>
Glires
Mammalia
Chordata
Vertebrata <Metazoa>
Rodentia
Organism or Virus
Thing
Provenance Metadata About This Resource Record
workflow state
Published
contributor
fcoldren
created
2014-03-14T18:18:56.025-04:00
creator
laavanya (Laavanya Sankaranarayanan)
modified
2014-04-08T13:29:37.219-04:00