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kdel
eagle-i ID
http://eagle-i.itmat.upenn.edu/i/00000144-e05d-4962-84bf-da3d80000000
Resource Type
Properties
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Resource Description
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Mice lack the ability to produce immunoglobulin (Ig) kappa light chains by targeted deletion of J kappa and C kappa gene segments and the intervening sequences.
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Additional Name
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kappa deleted
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Related Disease
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hypersensitivity reaction type II disease
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Related Publication or Documentation
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Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion.
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Website(s)
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http://www.informatics.jax.org/allele/key/9419
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Parental Strain Name
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B6
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Genetic Alteration(s)
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Igk[tm1Dhu]
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Phenotype Findings
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Reduced antibody light chain diversity
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Location
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Luning Prak Laboratory
