eagle-i The University of PennsylvaniaThe University of Pennsylvania
See it in Search
This page is a preview of the following resource. Continue onto eagle-i search using the button on the right to see the full record.

kdel

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/00000144-e05d-4962-84bf-da3d80000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    Mice lack the ability to produce immunoglobulin (Ig) kappa light chains by targeted deletion of J kappa and C kappa gene segments and the intervening sequences.
  2. Additional Name
    kappa deleted
  3. Related Disease
    hypersensitivity reaction type II disease
  4. Related Publication or Documentation
    Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion.
  5. Website(s)
    http://www.informatics.jax.org/allele/key/9419
  6. Parental Strain Name
    B6
  7. Genetic Alteration(s)
    Igk[tm1Dhu]
  8. Phenotype Findings
    Reduced antibody light chain diversity
  9. Location
    Luning Prak Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016