Weljie Lab

eagle-i ID

Resource Type

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1. Resource Description

   "The Weljie Lab is located in the Department of Pharmacology at the University of Pennsylvania. Our lab is at the forefront of metabolomics technologies to examine biological problems in a translational medicine context. Metabolomics is a growing sub-field of systems biology centered on the study of small biological molecules in biological fluids and tissues. Recent research suggests that analysis of metabolite concentrations in living systems is useful in disease diagnosis, prognosis, and predicting drug efficacy in a personalized medicine context. Our focus is on developing analytical methods to advance research in translational medicine. There is an intrinsic link between metabolism and function of the innate circadian clock system in numerous organisms and disease states, but the exact mechanism by which the clock controls mammalian metabolism is poorly understood. Our work seeks to fill this knowledge gap along with identifying biomarkers of cancer and environmental health."

2. PI

   Weljie, Aalim M., PhD

3. Affiliation

   Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania

4. Performs Technique

   Liquid chromatography-mass spectrometry

5. Performs Technique

   Nuclear magnetic resonance assay

6. Performs Technique

   Metabolite profiling

7. Performs Technique

   Mass spectrometry

8. Website(s)

   http://www.med.upenn.edu/weljielab/