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FLIPR Tetra screening system

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000014a-e3dd-9e42-af8a-04bf80000000

Resource Type

  1. Microplate reader

Properties

  1. Resource Description
    <strong>Measurement Technology:</strong> • Integrates liquid handling with rapid whole plate imaging of fluorescence and luminescence • Can read at sub-second intervals, which enables the kinetics of the response to be captured • Integrated pipettor enables successive liquid additions, providing an opportunity to detect agonists, antagonists, and allosteric modulators all in one assay <strong>Assays:</strong> 1. Intracellular Ca2+ flux: cell permeable Ca2+ sensitive fluorescent dye (e.g. cardiotoxicity); 2. Fatty acid or neurotransmitter uptake of fluorescence dyes. 3. Membrane potential: lipophilic, anionic, fluorescent dye that partitions across the cytoplasmic membrane of live cells based membrane potential.
  2. Additional Name
    Flouresence Imaging Plate Reader
  3. Manufacturer
    Molecular Devices, Inc.
  4. Website(s)
    https://www.moleculardevices.com/systems/flipr-tetra-high-throughput-cellular-screening-system
  5. Related Technique
    High throughput sample analysis
  6. Location
    High-Throughput Screening Core (Penn)
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2015-01-13T10:18:39.565-05:00
  4. creator
    fcoldren
  5. modified
    2016-04-25T16:07:19.758-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016