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FLIPR Tetra screening system

eagle-i ID


Resource Type

  1. Microplate reader


  1. Resource Description
    <strong>Measurement Technology:</strong> • Integrates liquid handling with rapid whole plate imaging of fluorescence and luminescence • Can read at sub-second intervals, which enables the kinetics of the response to be captured • Integrated pipettor enables successive liquid additions, providing an opportunity to detect agonists, antagonists, and allosteric modulators all in one assay <strong>Assays:</strong> 1. Intracellular Ca2+ flux: cell permeable Ca2+ sensitive fluorescent dye (e.g. cardiotoxicity); 2. Fatty acid or neurotransmitter uptake of fluorescence dyes. 3. Membrane potential: lipophilic, anionic, fluorescent dye that partitions across the cytoplasmic membrane of live cells based membrane potential.
  2. Additional Name
    Flouresence Imaging Plate Reader
  3. Manufacturer
    Molecular Devices, Inc.
  4. Website(s)
  5. Related Technique
    High throughput sample analysis
  6. Location
    High-Throughput Screening Core (Penn/CHOP)
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Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016