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Optical trap / Laser tweezers microscopes
eagle-i ID
http://eagle-i.itmat.upenn.edu/i/0000014b-07de-d971-af8a-04bf80000000
Resource Type
Properties
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Resource Description
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Optical tweezers microscopes for the measurement of nanometer-scale displacements and picoNewton-scale forces are available to Penn laboratories. These instruments are used for measuring biological forces (e.g., cell adhesion forces, protein-protein interactions, protein conformational changes, and other macromolecular associations) and manipulating objects in vitro and in the cytoplasm of live cells.
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Contact
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Ostap, E. Michael., PhD
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Access Restriction(s)
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Training by PMI faculty required.
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Related Publication or Documentation
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Force Generation in Single Conventional Actomyosin Complexes under High Dynamic Load
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Related Publication or Documentation
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Multi-step fibrinogen binding to the integrin (alpha)IIb(beta)3 detected using force spectroscopy
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Related Publication or Documentation
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Myosin I Can Act As a Molecular Force Sensor
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Developed by
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Penn Muscle Institute
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Location
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Advanced Optical and Force Microscopy Facility (Penn)
