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Optical trap / Laser tweezers access service

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Resource Type

  1. Access service


  1. Fee for service
  2. Resource Description
    Optical tweezers microscopes for the measurement of nanometer-scale displacements and picoNewton-scale forces are available to Penn laboratories. These instruments are used for measuring biological forces (e.g., cell adhesion forces, protein-protein interactions, protein conformational changes, and other macromolecular associations) and manipulating objects in vitro and in the cytoplasm of live cells.
  3. Contact
    Ostap, E. Michael., PhD
  4. Related Resource
    Optical trap / Laser tweezers microscopes
  5. Access Restriction(s)
    Training by PMI faculty required.
  6. Service Provided by
    Advanced Optical and Force Microscopy Facility (Penn)
  7. Related Publication or Documentation
    Force Generation in Single Conventional Actomyosin Complexes under High Dynamic Load
  8. Related Publication or Documentation
    Multi-step fibrinogen binding to the integrin (alpha)IIb(beta)3 detected using force spectroscopy
  9. Related Publication or Documentation
    Myosin I Can Act As a Molecular Force Sensor
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Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016