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Wnt7b(lacZ-/-)

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000014e-6927-025e-5109-12c780000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    "A targeting vector was designed to replace exon 1, including the ATG, with a lacZ-neo cassette. Unexpectedly, transcripts contining exons 3 and 4 were detected at low levels. LacZ expression recapitulates the endogenous expression pattern."
  2. Related Publication or Documentation
    Wnt7b regulates mesenchymal proliferation and vascular development in the lung
  3. Related Publication or Documentation
    WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature
  4. Related Publication or Documentation
    Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway
  5. Related Publication or Documentation
    Wnt ligands signal in a cooperative manner to promote foregut organogenesis
  6. Website(s)
    http://www.informatics.jax.org/allele/key/43705
  7. Genetic Alteration(s)
    Wnt7b[tm1Eem]
  8. Location
    Morrisey Lab
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2015-07-07T11:35:05.481-04:00
  4. creator
    fcoldren
  5. modified
    2015-07-10T14:24:13.712-04:00

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016