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Wnt2 mutant

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000014e-696c-f0db-5109-12c780000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    "The coding region in exon 1 was replaced with a reverse tet-activator (rtTA). A downstream FRT flanked neo cassette was removed by germ line, flp mediated recombination."
  2. Related Publication or Documentation
    Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut
  3. Related Publication or Documentation
    Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression
  4. Website(s)
    http://www.informatics.jax.org/allele/key/569989
  5. Genetic Alteration(s)
    Wnt2[tm1.1(rtTA)Eem]
  6. Location
    Morrisey Lab
 
RDFRDF
 
Inferred Types from the eagle-i Ontology (What is an ontology?)
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2015-07-07T12:51:12.303-04:00
  4. creator
    fcoldren
  5. modified
    2015-07-14T16:08:51.656-04:00
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016