Wnt2 mutant

eagle-i ID

Resource Type

Properties

1. Resource Description

   "The coding region in exon 1 was replaced with a reverse tet-activator (rtTA). A downstream FRT flanked neo cassette was removed by germ line, flp mediated recombination."

2. Related Publication or Documentation

   Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut

3. Related Publication or Documentation

   Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression

4. Website(s)

   http://www.informatics.jax.org/allele/key/569989

5. Genetic Alteration(s)

   Wnt2[tm1.1(rtTA)Eem]

6. Location

   Morrisey Lab