Foxp1(+/-) mice

eagle-i ID

Resource Type

Properties

1. Resource Description

   "Exons 12, 13, and 14, that encode the forkhead DNA-binding domain, were replaced with a Neo cassette via homologous recombination. RT-PCR and immunohistochemistry confirmed absence of mRNA in embryos and protein in heart tissue."

2. Related Publication or Documentation

   Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation

3. Related Publication or Documentation

   Foxp2 and Foxp1 cooperatively regulate lung and esophagus development

4. Related Publication or Documentation

   Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons

5. Website(s)

   http://www.informatics.jax.org/allele/key/33574

6. Genetic Alteration(s)

   Foxp1[tm1Eem]

7. Location

   Morrisey Lab