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MDR

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/00000150-b534-2516-b538-857980000000

Resource Type

  1. Algorithmic software suite

Properties

  1. Related grant number
    AI59694
  2. Related grant number
    LM009012
  3. Resource Description
    "Multifactor Dimensionality Reduction (MDR) is a nonparametric and genetic model-free machine learning alternative to logistic regression for detecting and characterizing nonlinear interactions among discrete genetic and environmental attributes. The MDR method combines attribute selection, attribute construction, and classification with cross-validation and permutation testing to provide a comprehensive and powerful approach to detecting epistasis. MDR has been successfully applied to numerous different diseases and is currently being adapted to genome-wide association studies (GWAS)."
  4. Additional Name
    Multifactor Dimensionality Reduction
  5. Used by
    Computational Genetics Laboratory
  6. Version
    3.0.2
  7. Software purpose
    Molecular interaction network analysis objective
  8. Related Publication or Documentation
    A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility
  9. Website(s)
    http://www.epistasis.org/index-3.html
  10. Website(s)
    http://www.multifactordimensionalityreduction.org
  11. Related Technique
    Bioinformatics analysis
  12. Software license
    GNU General Public License
  13. Coded in
    Java
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2015-10-29T16:06:01.743-04:00
  4. creator
    fcoldren
  5. modified
    2015-11-02T10:27:02.406-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016