CD59(-/-)

eagle-i ID

Resource Type

Properties

1. Resource Description

   "Exon 2, which encodes the initiator methionine and the N-terminal signal peptide, was replaced with a neo cassette." Cryopreserved - no active mice

2. Additional Name

   CD59 KO

3. Related Publication or Documentation

   Critical protection from renal ischemia reperfusion injury by CD55 and CD59

4. Related Publication or Documentation

   Crry, but not CD59 and DAF, is indispensable for murine erythrocyte protection in vivo from spontaneous complement attack

5. Related Publication or Documentation

   Regulation of Toll-like receptor–mediated inflammatory response by complement in vivo

6. Website(s)

   http://www.informatics.jax.org/allele/MGI:2675293

7. Parental Strain Name

   Balb/c

8. Biological process studied

   Immune system process

9. Genetic Alteration(s)

   Cd59a[tm1Song]

10. Location

    Wen-Chao Song Laboratory