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Xenograft services

eagle-i ID


Resource Type

  1. Material modification service


  1. Fee for service
  2. Resource Description
    "The SCXC offers a wide variety of xenograft services from training to full-service experiments. The Core maintains a large breeding colony of immune-deficient (NSG) mice for users xenograft studies. We also offer human immune system (CD34-transplanted) NSG mice for a wide variety of studies ranging from gene therapy to HIV. Experimental animals are housed in dedicated BSL-2 animal barrier space equipped for whole body irradiation and all necessary procedures and survival surgeries. Currently established xenograft models include normal human CD34 and leukemia engraftment, human iPS and ES-derived teratomas, human skin grafting, orthotopic human ovarian, hepatic and pancreatic tumor cell injections, renal capsule implantation. We also offer access to a dedicated optical/fluorescence (IVIS Spectrum) imaging system located within the Core's BSL-2 space." Xenograft services include: Blood glucose measurement Busulfan Conditioning Injections (iv, ip, sc) in Mice Intra bone injection Intra Cranial injections Irradiation Mouse body scoring Mouse bone marrow aspirate Mouse health monitoring Mouse Weighting Necropsy service Oral Gavage Orthotopic liver injection Orthotopic ovarian injection Orthotopic Pancreatic injection Osmotic Pump Implant Oxivir Phlebotomy Samples Renal capsule injection Topical drug application Tumor Measurements
  3. Service Fee URL
  4. Related Resource
    Immune-deficient (NSG) mice
  5. Related Resource
    BLT mice
  6. Topic
  7. Topic
  8. Topic
  9. Service Provided by
    Stem Cell & Xenograft Core (Penn)
  10. Website(s)
  11. Related Technique
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Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016