GIANT GWAS 2010-2013 Summary Statistics: waist-hip ratio adjusted for BMI

eagle-i ID

Resource Type

Properties

1. Resource Description

   Summary data from the GIANT consortium 2010-2013 meta-analyses of Genome-wide Association (GWA) data include p-values and direction of effect at over 2 million directly genotyped or imputed single nucleotide polymorphisms (SNPs). Allele frequency data was not released to prevent the possibility of identifying individuals from the summary results. In the discovery stage, up to 2,850,269 imputed and genotyped single nucleotide polymorphisms (SNPs) were examined in 32 GWA studies comprising up to 77,167 participants informative for anthropometric measures of body fat distribution. SNPs representing the top 16 independent regions of association were evaluated in 29 additional, independent studies (up to 113,636 individuals).

2. Access Restriction(s)

   Please cite the related publication

3. Used by

   Voight Laboratory

4. Data Input

   Waist-hip ratio association summary statistics

5. Topic

   Homo sapiens

6. Related Publication or Documentation

   Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

7. Website(s)

   https://www.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium_data_files

8. Related Technique

   SNP genotyping assay

9. Developed by

   Genetic Investigation of ANthropometric Traits Consortium

10. Part of Collection

    GIANT consortium association summary statistics