Genome Wide Associations Scans for HDL-C, LDL-C and triglycerides

eagle-i ID

Resource Type

Properties

1. Resource Description

   Genotype imputation and meta-analysis were used to combine three genome-wide scans totaling 8,816 individuals. The 11 independent variants associated with increased LDL cholesterol concentrations in the study also showed increased frequency in a sample of coronary artery disease cases versus controls.

2. Access Restriction(s)

   Please cite the related publication

3. Used by

   Voight Laboratory

4. Data Input

   LDL-C meta-analysis results association summary statistics

5. Data Input

   HDL-C meta-analysis results association summary statistics

6. Data Input

   Triglycerides meta-analysis results association summary statistics

7. Topic

   Homo sapiens

8. Topic

   coronary stenosis

9. Topic

   Lipid metabolic process

10. Related Publication or Documentation

    Newly identified loci that influence lipid concentrations and risk of coronary artery disease

11. Website(s)

    http://csg.sph.umich.edu/abecasis/public/lipids/

12. Related Technique

    SNP genotyping assay