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GPC association summary statistics

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/00000155-e19c-362e-c956-e86e80000000

Resource Type

  1. Resource Collection

Properties

  1. Resource Description
    "<strong>Big Five personality traits</strong> In the first phase of the project, we conducted a meta-analysis of Genome-Wide Association Studies (GWAS) in 10 discovery cohorts (N=17375) and 5 replication cohorts (N=3294) for each of the Big Five personality traits as assessed with the NEO-Five Factor Inventory (Neuroticism, Extraversion, Openness to Experience, Agreeableness and Conscientiousness). HAPMAP build 36 release 22 was used as a reference panel to impute missing genotypes in cohorts. Results of the meta-analysis are available under GPC-1. Please carefully read the ReadmeGPC-1.pdf file when downloading the data. If data end up in a scientific publication (e.g. scientific article, presentation at meeting), please make sure you cite the appropriate publications (see under References). <strong>Harmonized Neuroticism and Extraversion</strong> In the second phase of the project, we conducted a meta-analysis of GWAS in 29 discovery cohorts (N=63661) and 1 replication cohort (N=9786) for two harmonized personality traits: Neuroticism and Extraversion. Personality item data from 9 different inventories were harmonized by applying Item Response Theory (IRT). This was followed by a meta-analysis of GWAS results for the harmonized Neuroticism and Extraversion scores. 1000G build 37 phase 1 v3 was used as a reference panel to impute missing genotypes in cohorts. Results of the meta-analysis are available under GPC-2. Please carefully read the ReadmeGPC-2.pdf file when downloading the data. If data end up in a scientific publication (e.g. scientific article, presentation at meeting), please make sure you cite the appropriate publications (see under References)."
  2. Website(s)
    http://www.tweelingenregister.org/GPC/
  3. Developed by
    Genetics of Personality Consortium
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    fcoldren
  3. created
    2016-07-12T20:18:48.060-04:00
  4. creator
    fcoldren
  5. modified
    2016-07-12T20:51:36.632-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016