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Inducible Bmal1 Knockout

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000016c-d8f2-e89b-ca32-d9ac80000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    Tamoxifen inducible global Bmal1 KO. The Bmal1f/f floxed mice were crossed with a tamoxifen-inducible universal Cre (EsrCre) mice or NestinCre mice (Jackson Laboratories, Bar Harbor, ME) to yield Bmal1f/f-EsrCre mice and Bmal1f/f-NestinCre (nKO) mice, respectively. To generate inducible Bmal1 knockout (iKO) mice, 3m old (unless specified) Bmal1f/f-EsrCre mice were treated with tamoxifen as previously described.
  2. Contact
    Teegarden, Sarah., PhD
  3. Related Publication or Documentation
    Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival
  4. Biological process studied
    circadian rhythm
  5. Location
    FitzGerald Lab
 
RDFRDF
 
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Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    ggrant (Gregory Grant)
  3. created
    2019-08-28T12:03:22.360-04:00
  4. creator
    ggrant (Gregory Grant)
  5. modified
    2020-02-13T11:39:12.291-05:00
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