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COX Reversa

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000016c-e2e5-a20e-ac0d-7d5c80000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    COX genes switched A COX-1>COX-2 mouse strain on a mixed C57BL/6×129/Sv genetic background was established previously by replacing most of exons 1–9 of Ptgs2 with the entire Ptgs1 cDNA and cryo-recovered from JAX (#008104). These mice were backcrossed with the C57BL/6 strain for 10 generations. Cross-breeding of COX-1>COX-2 and COX-2>COX-1 mice produces Reversa mice.
  2. Contact
    Teegarden, Sarah., PhD
  3. Related Publication or Documentation
    Flipping the cyclooxygenase (Ptgs) genes reveals isoform-specific compensatory functions.
  4. Location
    FitzGerald Lab
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    ggrant (Gregory Grant)
  3. created
    2019-08-30T10:23:21.966-04:00
  4. creator
    ggrant (Gregory Grant)
  5. modified
    2019-09-27T12:19:54.946-04:00
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016