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T cell-specific COX2 Knockout

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/0000016c-e331-f657-ac0d-7d5c80000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    CD4/COX2 KO Mice with the COX-2 gene flanked with 2 LoxP sites, COX-2f/f mice on a mixed 129Sv/B6 background (∼75% B6, ∼25% 129Sv) were crossed with B6 CD4Cre mice (Taconic, Hudson, NY) to obtain CD4Cre/COX-2f/+ mice, which then were backcrossed with COX-2f/f to create CD4Cre/COX-2f/f mice. These mice were crossed with COX-2f/f to generate CD4Cre/COX-2f/f mice as T cell-specific COX-2-deficient mice (TCKOs).
  2. Contact
    Teegarden, Sarah., PhD
  3. Related Disease
    cardiovascular system disease
  4. Related Publication or Documentation
    Targeted Deletions of Cyclooxygenase-2 and Atherogenesis in Mice
  5. Biological process studied
    Regulation of biological process
  6. Location
    FitzGerald Lab
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    ggrant (Gregory Grant)
  3. created
    2019-08-30T11:46:16.076-04:00
  4. creator
    ggrant (Gregory Grant)
  5. modified
    2020-02-13T10:52:13.977-05:00
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016