KO mice

eagle-i ID

Resource Type

Properties

1. Fee for service

   Yes

2. Resource Description

   Generation of knock-out (KO) mice usually requires the design of the targeting strategy, production of Cas9 mRNA and 2 or more gRNAs, microinjection of one-cell embryos, and screening of founder mice. Double, triple or quadruple KO mice of different genes can be accomplished with one injection.

3. Service Fee URL

   https://pathbio.med.upenn.edu/crispr/site/fees/

4. Service Provided by

   CRISPR/Cas9 Mouse Targeting Core

5. Website(s)

   https://pathbio.med.upenn.edu/crispr/site/services/