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Muscle Physiology Assessment Core

eagle-i ID

http://eagle-i.itmat.upenn.edu/i/00000175-ae29-3da1-e82c-110080000000

Resource Type

  1. Material analysis service

Properties

  1. Resource Description
    1) In Vitro Muscle Evaluation: Mechanical evaluation (i.e. contraction time, relaxation time, absolute twitch and tetanic forces, specific twitch and tetanic forces, Force drop after eccentric contractions (ECC), post-ECC dye exclusion studies, fatigue & recovery studies, metabolic studies (i.e. contraction mediated glucose uptake). 2) In Vivo Exercise Evaluation: Rota –Rod performance, Grip Strength, Voluntary exercise (Cages), Treadmill with uphill/downhill exercise studies, Hypoxic exercise tolerance. 3) In Vivo Muscle Evaluation: Electromyograms (EMG), Nerve stimulation evoked muscle contractions for absolute twitch and tetanic forces, specific twitch and tetanic forces, Force drop after eccentric contractions (ECC), repetitive stimulations for myasthenia studies, fatigue & recovery studies. Shivering thermogenesis, muscle and brown fat heat production. 4) In Vivo Respiratory Evaluation: Whole body plethysmography (Respiratory Rate, Tidal Volume, Minute Volume), Hypoxic Ventilatory Response (HVR), Hypercapnic Ventilatory Response (HCVR), Hypoxic exercise tolerance, Phrenic nerve recordings with intercostals wall EMGs. 5) Preparation of post-evaluation muscle / tissues for morphological analyses (for frozen, fixed and EM sections).
  2. Service Provided by
    Penn Muscle Institute
  3. Website(s)
    https://www.med.upenn.edu/pmi/facilities.html
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    ggrant (Gregory Grant)
  3. created
    2020-11-09T13:01:14.530-05:00
  4. creator
    ggrant (Gregory Grant)
  5. modified
    2020-11-09T13:01:18.913-05:00
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016