he Analytical Neurochemistry Core (ANC) will enable users to identify and quantify changes in brain biochemistry. Analyses are performed: (a) In vitro; (b) In pre-clinical animal models of intellectual and developmental disabilities (IDD); and (c) In vivo, in human patients. Users have access to a broad repertoire of analytical services, as well as expert advice with regard to experimental design and data interpretation.
-- Quantitation of amino acids and biogenic amines (Director: Robinson; Contact: Liz Krizman: firstname.lastname@example.org)
-- Kinetic studies of flux through metabolic pathways using stable isotopes as tracers and mass spectrometry to measure isotopic enrichment (Director: Nissim)
-- Qualitative and quantitative mass spectroscopic analyses of proteins/peptides and their modifications (Director: Ischiropoulos; Contact: Steve Seeholzer, PhD: email@example.com)
-- Bioenergetic assays of mitochondrial function (Director: Falk; Subcore Contact: Jenny Kong: firstname.lastname@example.org)