eagle-i University of PennsylvaniaUniversity of Pennsylvania
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Youhai H. Chen Lab

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Instruments

Organisms and Viruses

  • c-Rel knock out ( Mus musculus )

  • MiR-21 knock out ( Mus musculus )

  • PDCD4 knock out ( Mus musculus )

  • TIPE and TIPE2 DKO ( Mus musculus )

  • Tipe(-/-) ( Mus musculus )

    "Tipe−/− mice were generated using gene trap technology to target Tipe gene in B6 ES cells. The gene-trapping vector is composed of a viral long terminal repeat, a splice acceptor site, a Neomycin-resistant gene, and a polyA tail that stops Tipe gene transcription. This disrupted Tipe gene allele results in a complete loss of the short isoform of Tipe mRNA and a truncated long isoform of Tipe mRNA that encodes the first N-terminal 24 aa."

  • TIPE2(-/-) ( Mus musculus )

    "Both exons of this gene locus were replaced by a neomycin resistance cassette. RT-PCR on bone marrow confirmed gene inactivation."

  • TIPE2(-/-) ( Mus musculus )

    "Both exons of this gene locus were replaced by a neomycin resistance cassette. RT-PCR on bone marrow confirmed gene inactivation."

  • Tipe3(-/-) ( Mus musculus )

    Tipe3+/- mice were purchased from the Knockout Mouse Project Repository.

Reagents


Last updated: 2016-02-15T12:48:52.944-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016