eagle-i University of PennsylvaniaUniversity of Pennsylvania
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Laboratory of Michael Cancro

Summary:

Our laboratory is currently pursuing studies focused on mechanisms of B cell homeostasis and how these impact autoimmunity and aging. These have led to the characterization of a novel receptor for BLyS, a TNF family member that controls B cell numbers and determines the stringency of B cell selection.

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Organisms and Viruses

  • Bcl-xL transgenic ( Mus musculus )

    This line is used to assess cell survival

  • TACI-/- ( Mus musculus )

    This is a global knockout


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Last updated: 2016-03-01T17:11:47.607-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016